APLF (phospho Ser116) Rabbit Polyclonal Antibody
Product Specifications
Background
C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks (Iles et al., 2007 [PubMed 17353262]) .[supplied by OMIM, Mar 2008], domain:The FHA-like domain mediates interaction with XRCC1 and XRCC4., function:Involved in single-strand and double-strand DNA break repair., PTM:Phosphorylated in an ATM-dependent manner upon double-strand DNA break., similarity:Contains 1 FHA-like domain., similarity:Contains 2 C2H2-type zinc fingers., subcellular location:Colocalizes with XRCC1 at sites of DNA damage., subunit:Interacts with XRCC1. May also interact with XRCC4 and XRCC5.
Product Name Alternative
APLF; C2orf13; PALF; XIP1; Aprataxin and PNK-like factor; Apurinic-apyrimidinic endonuclease APLF; PNK and APTX-like FHA domain-containing protein; XRCC1-interacting protein 1
Gene Name
APLF
Gene ID
200558
Swiss Prot
Q8IW19
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC, ICC/IF, ELISA
Purification
Affinity purification
Dilution
IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:5000-1:10000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Phosphorylated
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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