ATPBD3 Rabbit Polyclonal Antibody
Product Specifications
Background
Function:Plays a central role in 2-thiolation of mcm (5) S (2) U at tRNA wobble positions of tRNA (Lys), tRNA (Glu) and tRNA (Gln) . Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position., pathway:tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis., similarity:Belongs to the ttcA family. CTU1/NCS6/ATPBD3 subfamily., subunit:Component of a complex at least composed of URM1, CTU2/NCS2 and ATPBD3/NCS6. May for a heterodimer with CTU2/NCS2., function:Plays a central role in 2-thiolation of mcm (5) S (2) U at tRNA wobble positions of tRNA (Lys), tRNA (Glu) and tRNA (Gln) . Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position., pathway:tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis., similarity:Belongs to the ttcA family. CTU1/NCS6/ATPBD3 subfamily., subunit:Component of a complex at least composed of URM1, CTU2/NCS2 and ATPBD3/NCS6. May for a heterodimer with CTU2/NCS2.
Product Name Alternative
CTU1; ATPBD3; NCS6; Cytoplasmic tRNA 2-thiolation protein 1; ATP-binding domain-containing protein 3; Cancer-associated gene protein; Cytoplasmic tRNA adenylyltransferase 1
Gene Name
CTU1
Gene ID
90353
Swiss Prot
Q7Z7A3
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
36kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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