AF10 Rabbit Monoclonal Antibody

Product Specifications

Background

Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation (PubMed:26439302) .

Product Name Alternative

MLLT10; AF10; Protein AF-10; ALL1-fused gene from chromosome 10 protein

Gene Name

AF10

Gene ID

8028

Swiss Prot

P55197

Host

Rabbit

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC

Purification

Affinity Purification

Dilution

WB 1:500-1:1000, IHC 1:50-1:100

Form

Liquid

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Modification

Unmodified

Molecular Weight

Calculated MW: 113 kDa; Observed MW: 140 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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