Phospho-eIF4B (S406) Recombinant Rabbit Monoclonal Antibody [JE58-32]
Eukaryotic translation initiation factor 4B is a protein that in humans is encoded by the EIF4B gene. eIF4B has been shown to interact with and stimulate the activity of eIF4A and bind to the eIF3 complex through the eIF3A subunit. This interaction results in the recruitment of the eukaryotic small ribosomal subunit (40S) to the mRNA which will in turn set the stage for the later steps leading to elongation.
Product Specifications
Product Name Alternative
Abbreviation
EIF4B
Swiss Prot
P23588 Human, Q8BGD9 Mouse, Q5RKG9 Rat
Cellular Locus
cytosol, eukaryotic translation initiation factor 4F complex.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide corresponding to residues surrounding Ser406 of human eIF4B protein.
Isotype
IgG
Clone
JE58-32
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
NIH/3T3 cell lysate, HeLa cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:2,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 69 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
CAS Number
9000-83-3
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