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CD89 Rabbit Monoclonal Antibody

Product Specifications

Background

Cell localization:[Isoform A.1]: Cell membrane; Single-pass type I membrane protein.; [Isoform A.2]: Cell membrane; Single-pass type I membrane protein.; [Isoform A.3]: Cell membrane; Single-pass type I membrane protein.; [Isoform B]: Secreted.; [Isoform B-delta-S2]: Secreted..This gene is a member of the immunoglobμLin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimμLation of the release of inflammatory mediators. MμLtiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, JμL 2008]

Product Name Alternative

FCAR; CD89; ImmunoglobμLin alpha Fc receptor ; IgA Fc receptor; CD antigen CD89

Gene Name

FCAR; CD89

Gene ID

2204

Swiss Prot

P24071

Host

Rabbit

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, FC, IP

Purification

Protein A

Dilution

WB 1:1000-1:5000, IHC 1:100-1:300, ICC/IF 1:100-1:300, FC 1:100-1:300, IP 1:50-1:100

Form

Liquid

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Modification

Unmodified

Molecular Weight

CalcμLated MW:; Observed MW:32kD

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG, Kappa

Available Sizes

Curated Selection

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