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NOP10 Rabbit Monoclonal antibody

Product Specifications

Background

This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA2 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nop10p.

Product Name Alternative

DKCB1; NOLA3; NOP10P

Gene Name

NOP10

Gene ID

55505

Swiss Prot

Q9NPE3

Host

Rabbit

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC

Field of Research

Epigenetics and Nuclear Signaling

Purification

Affinity Purified

Dilution

WB 1:500-1:1000, IHC 1:50-1:100

Form

Liquid

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Modification

Unmodified

Molecular Weight

Calculated MW: 8 kDa; Observed MW: 8 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Product Datasheet

https://assets.enkilife.com/files/antibody/AMRe03118_Enkilife_EN.pdf

Isotype

IgG

Available Sizes

Curated Selection

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