DCB-3503
Product Specifications
CAS Number
87302-58-7
Target
Others|||HSP|||CDK
Related Pathways
Metabolism|||Cytoskeletal Signaling|||Cell Cycle/Checkpoint|||Others
Bioactivity
Tylophorine analog DCB-3503 is a potential anticancer and immunosuppressive agent. DCB-3503 suppresses the translation of cellular regulatory proteins, including cyclin D1, at the elongation step. DCB-3503 allosterically regulates the ATPase and chaperone activities of HSC70 by promoting ATP hydrolysis in the presence of specific RNA binding motifs (AUUUA) of cyclin D1 mRNA.
Smiles
O[C@H]1C=2C(=C3C(=C4C2C=C(OC)C(OC)=C4)C=C(OC)C(OC)=C3)CN5[C@]1(CCC5)[H]
Molecular Formula
C24H27NO5
Molecular Weight
409.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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