Recombinant Human APN Protein (C-6His)

Product Specifications

Background

ANPEP gene encodes aminopeptidase N (APN) also known as microsomal aminopeptiase, alanyl aminopeptidase, aminopeptidase M, CD13, or membrane protein p161, is a member of the peptidase M1 family. Widely expressed in many cells, tissues and species, APN cleaves the N-terminal amino acids from bioactive peptides, leading to their inactivation or degradation. Probably plays a role in regulating growth and differentiation of early B-lineage cells. It also may play a role in the catabolic pathway of the renin-angiotensin system. It degrades vasoconstricting angiotensin II into angiotensin III and therefore helps to regulate blood pressure.

Product Name Alternative

Aminopeptidase N; ANPEP; AP-M; APN; AP-N; CD13 antigen; CD13; CD13APN; PEPN; PEPNhAPN

Accession Number

P15144

Host

Human Cells

Endotoxin

Please contact with the lab for this information

Purity

Greater than 95% as determined by reducing SDS-PAGE

Form

Liquid

Molecular Weight

103.5 KDa

Shipping Conditions

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Storage Conditions

Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Formulation

Supplied as a 0.2 μm filtered solution of PBS, 5% Trehalose, pH 7.4.

Construct

Recombinant Human Aminopeptidase N is produced by our Mammalian expression system and the target gene encoding Lys69-Lys967 is expressed with a 6His tag at the C-terminus.