MLKL (phospho-S345) polyclonal antibody
Product Specifications
Background
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process.
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Mixed lineage kinase domain-like protein; hMLKL
Swiss Prot
Q9D2Y4
Reactivity
Mouse, Rat
Immunogen
Synthetic phospho-peptide corresponding to residues surrounding Ser345 of human MLKL.
Conjugation
Unconjugated
Applications
WB, IF
Dilution
WB,1:500 - 1:1000|IF,1:50 - 1:200
Purity
Modification
Phosphorylation
Molecular Weight
54 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
MLKL (phospho-S345) polyclonal antibody detects endogenous levels of MLKL protein only when phosphorylated at S345.
Applications Notes
Western blot analysis of MLKL (Phospho-S345) expression in mouse kidney (A), rat kidney (B) whole cell lysates.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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