Valiolamine

Valiolamine, an aminocyclitol, is an alpha-glucosidase inhibitor. Valiolamine has potent alpha-glucosidase inhibitory activity against porcine intestinal sucrase, maltase and isomaltase. Valiolamine binds to porcine intestinal maltase and sucrase with Ki values of 350 nM and 30 nM, respectively[1].

Product Specifications

CAS Number

[83465-22-9]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/valiolamine.html

Purity

98.0

Solubility

H2O : 175 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@@](C[C@@H](N)[C@H]([C@@H]1O)O)(CO)O

Molecular Formula

C7H15NO5

Molecular Weight

193.20

Precautions

H302, H315, H319, H335

References & Citations

[1]Y Kameda, et al. Valiolamine, a New Alpha-Glucosidase Inhibiting Aminocyclitol Produced by Streptomyces Hygroscopicus. J Antibiot (Tokyo) . 1984 Nov;37 (11) :1301-7.