North-methanocarbathymidine

North-methanocarbathymidine (N-MCT) is a potent antiviral agent. North-methanocarbathymidine inhibits DNA synthesis. North-methanocarbathymidine demonstrates potent antiviral activity against HSV-1, HSV-2 and KSHV. North-methanocarbathymidine exhibits anticancer activity against colon adenocarcinoma expressing HSV-tk[1].

Product Specifications

CAS Number

[156126-12-4]

Product Name Alternative

N-MCT

UNSPSC

12352005

Target

DNA/RNA Synthesis; HSV

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection

Smiles

O=C1NC(C(C)=CN1[C@@H]2[C@@]3([H])C[C@@]3(CO)[C@@H](O)C2)=O

Molecular Formula

C12H16N2O4

Molecular Weight

252.27

References & Citations

[1]Marquez VE, et al. The history of N-methanocarbathymidine: the investigation of a conformational concept leads to the discovery of a potent and selective nucleoside antiviral agent. Antiviral Res. 2006 Sep;71 (2-3) :268-75.