TCS 401 (free base)
TCS 401 free base is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B) .
Product Specifications
CAS Number
243967-42-2
UNSPSC
12352211
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/tcs-401-free-base.html
Smiles
O=C(C(NC1=C(C(O)=O)C(CCNC2)=C2S1)=O)O
Molecular Formula
C10H10N2O5S
Molecular Weight
270.26
References & Citations
[1]Du ZD, et al. Protein tyrosine phosphatase 1B regulates the activity of retinal pigment epithelial cells. Mol Vis. 2015 May 1;21:523-31.|[2]Ponnusamy M, et al. Necrotic renal epithelial cell inhibits renal interstitial fibroblast activation: role of protein tyrosine phosphatase 1B. Am J Physiol Renal Physiol. 2013 Mar 15;304 (6) :F698-709.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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