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TNKS-2-IN-1

TNKS-2-IN-1 is a TNKS-2 inhibitor.TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM, respectively.TNKS-2-IN-1 has antimicrobial activity against E. coli and S. aureus.TNKS-2-IN-1 inhibits the release of IL-1β from the NLRP3 inflammasome (IC50: 5 μM) by inhibiting IL-1β release from ATP-stimulated J1A.774 cells.

Product Specifications

CAS Number

4765-59-7

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

267.24

Molecular Formula

C14H9N3O3

Notes

Research use only, not for human use.

Receptor

Wnt/beta-catenin | PARP | Antibiotic

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