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(1S,2R) -Alicapistat

(1S,2R) -Alicapistat ((1S,2R) -ABT-957) is a highly efficient, orally active compound that selectively inhibits human calpains 1 and 2, showing promise for Alzheimer's disease (AD) therapy . It effectively addresses the metabolic liability associated with carbonyl reduction and demonstrates potent inhibition of calpain 1 with an IC50 value of 395 nM .

Product Specifications

CAS Number

2221010-57-5

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

433.5

Molecular Formula

C25H27N3O4

Notes

Research use only, not for human use.

Receptor

Cysteine Protease

Available Sizes

Frequently Asked Questions

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