M-PEG6-azide

M-PEG6-azide is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . m-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

[1043884-49-6]

Product Name Alternative

AT2 receptor agonist C21

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/m-peg6-azide.html

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

COCCOCCOCCOCCOCCOCCN=[N+]=[N-]

Molecular Formula

C13H27N3O6

Molecular Weight

321.37

Precautions

H302, H315, H319, H335

References & Citations

[1]Gauzy, Laurence, et al. Cytotoxic agents comprising new tomaymycin derivatives and their therapeutic use. Patent WO2007085930A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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