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Ilorasertib hydrochloride

Ilorasertib hydrochloride (ABT-348 hydrochloride) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A (IC50s: 1 nM, 7 nM, 120 nM) . It also suppresses RET tyrosine kinase, PDGFRβ, and Flt1 (IC50s: 7 nM, 3 nM, and 32 nM) .

Product Specifications

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

525

Molecular Formula

C25H22ClFN6O2S

Notes

Research use only, not for human use.

Receptor

Aurora Kinase

CAS Number

1847485-91-9

Available Sizes

Curated Selection

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