Clemeprol
Clemeprol (BRL 14342) is an orally active Noradrenaline (NA) and 5-HT uptake blocker. Clemeprol inhibits 6- Hydroxydopamine (HY-B1081) -induced depletion of brain NA. Clemeprol exerts a dose-dependent inhibition of Reserpine (HY-N0480) -induced hypothermia. Clemeprol can be used in the research of depression[1][2].
Product Specifications
CAS Number
[71827-56-0]
Product Name Alternative
BRL 14342
UNSPSC
12352005
Target
Serotonin Transporter
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
CN(C)CC(O)C(C1=CC=CC=C1)C2=CC(Cl)=CC=C2
Molecular Formula
C17H20ClNO
Molecular Weight
289.80
References & Citations
[1]Clark JA, et al. Substituted 3-amino-1,1-diaryl-2-propanols as potential antidepressant agents. J Med Chem. 1979 Nov;22 (11) :1373-9.|[2]Clark MS, et al. Pharmacological and biochemical properties of BRL 14342, a novel potential antidepressant drug. Neuropharmacology. 1980 Dec;19 (12) :1207-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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