MLN120B
MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM) .MLN120B almost completely blocks the stimulation of MM.1S, U266, and INA6 cell growth, as well as IL-6 secretion from BMSCs, induced by multiple myeloma cell adherence to BMSCs [1]. MLN120B shows an inhibitory effect on LPS induced NF-κB activation in RAW267.4 cells.
Product Specifications
CAS Number
783348-36-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
366.8
Molecular Formula
C19H15ClN4O2
Notes
Research use only, not for human use.
Receptor
IKKβ
Available Sizes
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