VU 0361737
Product Specifications
CAS Number
1161205-04-4
Target
GluR
Applications
Neuronal Signaling
Smiles
COC1=C (C=CC (=C1) NC (=O) C2=CC=CC=N2) Cl
Molecular Formula
C13H11ClN2O2
Additionnal Information
VU 0361737 is a selective positive allosteric modulator (PAM) for mGlu4 receptor with EC50 of 240 nM and 110 nM at human and rat receptors, respectively, displays weak activity at mGlu5 and mGlu8 receptors, is inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors, can penetrate into CNS.
Storage Conditions
2 years -80 in solvent
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