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Histone H3 (mono+di+tri methyl K79) Rabbit mAb

This is a Histone H3 (mono+di+tri methyl K79) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.

Synonyms

H3 histone; HIST1H3A; Histone cluster 1; H3a; H3/l; HIST3H3; H3K79me1; H3K79me2; H3K79me3

Swiss Prot

P68431

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Histone H3 (mono+di+tri methyl K79)

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Recombinant Antibody

Applications

WB, IHC

Purification Method

Affinity purification

Assay Type

Antibody

Dilution

WB 1:500-1:1000, IHC 1:1000-1:2000

Buffer

Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Curated Selection

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