Antileishmanial agent-17

Antileishmanial agent-17 is a coumarin hybrid compound with antileishmanial effects (IC50 50 value of 0.40 μM against promastigote and 0.68 μM against amastigote, respectivley.

Product Specifications

CAS Number

[2934738-40-4]

UNSPSC

12352005

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antileishmanial-agent-17.html

Solubility

10 mM in DMSO

Smiles

O=C(NCCCCCCN1C=C(N=N1)CN2CCOCC2)C(C(O3)=O)=CC(C=C4)=C3C=C4OCCCC

Molecular Formula

C27H37N5O5

Molecular Weight

511.61

References & Citations

[1]Hassan NW, et al. Modulating leishmanial pteridine metabolism machinery via some new coumarin-1,2,3-triazoles: Design, synthesis and computational studies. Eur J Med Chem. 2023 May 5;253:115333.