Akt (pan) 1/2/3 Rabbit mAb
This is a Akt (pan) 1/2/3 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.
Synonyms
PKB; RAC; PRKBA; PKB-ALPHA; RAC-ALPHA; AKT1 ; AKT2; AKT3; Akt1/2/3; pan Akt
Swiss Prot
P31749/P31751/Q9Y243
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human AKT1/2/3
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC, ICC/IF, IP, FC
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:2000, IHC 1:50-1:200, ICC/IF 1:50-1:200, IP 1:50
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
56kDa
Host or Source
Rabbit
Isotype
IgG
Curated Selection
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