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Histone H2A.X (Phospho-Ser139) Rabbit mAb

This is a Histone H2A.X (Phospho-Ser139) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

Synonyms

H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X

Swiss Prot

P16104

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Phospho-Histone H2A.X (S139)

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Recombinant Antibody

Applications

WB, IHC, ICC/IF, IP

Purification Method

Affinity purification

Assay Type

Antibody

Dilution

WB 1:5000-1:10000, IHC 1:50-1:200, ICC 1:50-1:200, IP 1:30

Buffer

Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

15kDa

Host or Source

Rabbit

Isotype

IgG

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