IZCZ-3
IZCZ-3 is a potent c-MYC transcription inhibitor with antitumor activity[1].
Product Specifications
CAS Number
2223019-53-0
UNSPSC
12352005
Target
Autophagy; c-Myc
Type
Reference compound
Related Pathways
Apoptosis; Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/IZCZ-3.html
Purity
99.74
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
CN(CC1)CCN1C2=CC=C(C3=C(C4=CC=C(N5CCN(C)CC5)C=C4)N=C(C6=CC(C(C=CC=C7)=C7N8CC)=C8C=C6)N3C9=CC=C(OC)C=C9)C=C2
Molecular Formula
C46H49N7O
Molecular Weight
715.93
References & Citations
[1]Hu MH, et al. Discovery of a New Four-Leaf Clover-Like Ligand as a Potent c-MYC Transcription Inhibitor Specifically Targeting the Promoter G-Quadruplex. J Med Chem. 2018 Mar 22;61 (6) :2447-2459.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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