Recombinant Human ALDOA protein (His tag)
Product Specifications
Background
Fructose Bisphosphate Aldolase A (ALDOA) belongs to the class I fructose-bisphosphate aldolase family. ALDOA is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. In vertebrates, three forms of this ubiquitous glycolytic enzyme are found, Aldolase A in muscle, Aldolase B in liver and aldolase C in brain. Aldolase A Interacts with SNX9 and WAS. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. In addition, Aldolase A plays an important role in glycolysis and gluconeogenesis, it may also act as a scaffolding protein.
Abbreviation
ALDOA
Synonyms
ALDA; ALDOA; Fructose-Bisphosphate Aldolase A; Lung Cancer Antigen NY-LU-1; Muscle-Type Aldolase
UniProt
P04075
Accession Number
P04075
Expression System
E.coli
Tag
N-His
Sequence
Asp 18-Gly 273
Field of Research
Signal Transduction; Cancer; metabolism
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
28.0 kDa
Observed Molecular Weight
32 kDa
Species
Human
Available Sizes
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