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IFNL2 / IL28A Protein (His Tag)

Recombinant human Interferon-lambda2 (IFN-?2) is a 19.6 kDa protein containing 174 amino acid residues. IFN-lambda-1, -2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three IFN-lambdas uses a distinct receptor system composed of an IFN-lambdaR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14) . Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons.

Product Specifications

Synonyms

EG330496 Protein; If1ia1 Protein; Ifnl2 Protein; IL-28A Protein; Il28a Protein

Accession Number

NP_001019844.2

Reactivity

Mouse

Cross Reactivity

Mouse

Label

His-Tag

Assay Protocol

See Datasheet send with the product

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 95 % as determined by SDS-PAGE

Bioactivity

Measured in antiviral assay using HepG2 cells infected with vesicular stomatitis virus. The ED50 for this effect is typically 1-4 ng/mL.

Length

185

Form

Lyophilized or frozen liquid

Buffer

PBS, pH 7.4

Reconstitution

See Datasheet

Molecular Weight

28.5 kDa (glycosylated)

Storage Conditions

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Host or Source

HEK 293 cells

Frequently Asked Questions

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