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FGF-9

FGF-9 is a heparin binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-9 targets glial cells, astrocytes cells and other cells that express the FGFR 1c, 2c, 3b, 3c, and 4. Recombinant human FGF-9 is a 23.2 kDa protein consisting of 206 amino acid residues.

Product Specifications

Synonyms

FGF9; GAF; SYNS3; HBFG-9

NCBI Gene ID

2254

UniProt

P31371

Accession Number

NP_002001.1

Accession Number mRNA

NM_002010

Chromosomal Location

13q11-q12

Reactivity

Human

Cross Reactivity

Human, Mouse

Sequence

PLGEVGNYFG VQDAVPFGNV PVLPVDSPVL LSDHLGQSEA GGLPRGPAVT DLDHLKGILR RRQLYCRTGF HLEIFPNGTI QGTRKDHSRF GILEFISIAV GLVSIRGVDS GLYLGMNEKG ELYGSEKLTQ ECVFREQFEE NWYNTYSSNL YKHVDTGRRY YVALNKDGTP REGTRTKRHQ KFTHFLPRPV DPDKVPELYK DILSQS

Endotoxin

< 0.1 ng/µg of protein (< 1EU/µg)

Purity

> 95% by SDS-PAGE & HPLC analyses

Bioactivity

Determined by its ability to stimulate the proliferation of mouse balb/c 3T3 cells using a concentration range of 1.0-5.0 ng/ml.

Length

206

Form

Lyophilized

Molecular Weight

23.2 kDa

Host or Source

E. coli

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