Recombinant IGFBP3 Monoclonal Antibody
Product Specifications
Background
Insulin-like growth factor-binding protein 3 (IGFBP3) is a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Diseases associated with IGFBP3 include Insulin-Like Growth Factor I and Laron Syndrome.
Abbreviation
IGFBP3
UniProt
P17936
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human IGFBP3 fragment
Target
IGF-binding protein; Insulin-like Growth Factor Binding Protein; IBP; IGFBP3; BP-53; IBP3; IBP-3; IGF-binding protein 3; IGFBP-3; IGF-; Insulin-like Growth Factor Binding Protein 3
Clonality
Monoclonal,Recombinant
Clone
A496
Conjugation
Unconjugated
Applications
WB
Field of Research
Cell Biology; Signal Transduction; Cardiovascular; Metabolism; Cancer
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
32 kDa
Observed Molecular Weight
26, 43 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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