Recombinant Smad1 Monoclonal Antibody

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation.

JV4; MADH; MADR; MAD Homolog; Mad-Related Protein; Mothers Against DPP Homolog; Mothers Against Decapentaplegic Homolog; Transforming Growth Factor-Beta-Signaling Protein; hSMAD; BSP; BSP-1; BSP1; JV4-1; JV41; MADH1; MADR1; Smad1; hSMAD1; MAD Homolog 1; Mad-Related Protein 1; Mothers Against Decapentaplegic Homolog 1; Mothers Against DPP Homolog 1; SMAD 1; SMAD Family Member 1; Transforming Growth Factor-Beta-Signaling Protein 1; BSP1; BSP-1; JV41; JV4-1; MADH1; MADR1; SMAD family member 1; Smad1