Recombinant NRAS Monoclonal Antibody
Product Specifications
Background
This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
Abbreviation
NRAS
UniProt
P01111
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human NRAS protein
Target
ALPS; HRAS; NRAS; ALPS4; CMNS; N-ras; NCMS; NRAS1; NS6; GTPase NRas; GTPase; HRAS1; RASN; Transforming protein N-Ras; AV095280; N ras; N ras protein part 4; Neuroblastoma RAS viral (v ras) oncogene homolog; OTTHUMP00000013879; OTTMUSP00000023521; Transforming protein N Ras; v ras neuroblastoma RAS viral oncogene homolog; N-RAS
Clonality
Monoclonal,Recombinant
Clone
10A3
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction; Epigenetics and Nuclear Signaling; Cancer; Tags & Cell Markers
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:1000-1:5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product MSDS
https://789.bio/eb/dnlVhhoS
Calculated Molecular Weight
22 kDa
Observed Molecular Weight
22 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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