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CD20/MS4A1 Monoclonal Antibody

Product Specifications

Background

CD20 is a 297 amino acid (aa) non-glycosylated type III membrane protein that is the founding member of the MS4A tetraspanin protein family. It is expressed on pre-B, naïve and mature B lymphocytes and B-cell lymphomas. CD20 is associated with lipid rafts upon crosslinking, and appears to play a role in regulation of ion influx. The one extracellular segment of 48 aa shows 65% aa sequence identity between human and mouse CD20.

Abbreviation

MS4A1

UniProt

P11836

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD20/MS4A1 Protein

Target

LEU; CVID; B-lymphocyte antigen CD; Leukocyte surface antigen Leu; B-lymphocyte surface antigen B; Membrane-spanning 4-domains subfamily A member; MS4A1; B1; Bp35; CD20; CVID5; LEU-16; MS4A2; S7; B-lymphocyte antigen CD20; B-lymphocyte surface antigen B1; Leukocyte surface antigen Leu-16; Membrane-spanning 4-domains subfamily A member 1; Bp35; Ly-44; APY; ATOPY; B lymphocyte antigen CD20; B Lymphocyte Cell Surface Antigen B1; B-lymphocyte cell-surface antigen B1; Bp 35; CD 20; CD20 antigen; CD20 receptor; Fc epsilon receptor I beta chain; Fc Fragment of IgE high affinity I receptor for beta polypeptide; FCER1B; High affinity immunoglobulin epsilon receptor subunit beta; IgE Fc receptor subunit beta; IGEL; IGER; IGHER; LEU 16; LEU16; leukocyte surface antigen Leu 16; Ly44; Membrane spanning 4 domains A1; Membrane spanning 4 domains subfamily A member 2; MGC3969

Clonality

Monoclonal

Clone

12G5

Conjugation

Unconjugated

Applications

WB; IHC-P; IP

Field of Research

Immunology; Stem Cells; Cancer

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IHC-P 1:100-1:1000; IP 1-5 μL/mg of lysate

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

33 kDa

Observed Molecular Weight

36 kDa

Isotype

IgG1

Frequently Asked Questions

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