ERK2/MAPK1/MAPK2 Monoclonal Antibody
Product Specifications
Background
MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets.
Abbreviation
MAPK1
UniProt
P28482
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human ERK2/MAPK1/MAPK2 Protein
Target
ERK; MAPK1/MAPK; MAPK; MAPK1/MAPK3; ERK2; PRKM1; PRKM2; MAPK1; ERK 2; ERK-2; ERT1; Extracellular Signal Regulated Kinase 2; Extracellular signal-regulated kinase 2; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; MAPK 1; MAPK 2; MAPK2; mitogen-activated; mitogen-activated protein kinase 1; Mitogen-activated protein kinase 2; MK01; p38; p40; p41; p41mapk; P42MAPK; p42-MAPK; protein kinase; protein tyrosine kinase ERK2
Clonality
Monoclonal
Clone
2B10
Conjugation
Unconjugated
Applications
WB
Field of Research
Neuroscience; Signal Transduction; Stem Cells; Cancer
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
40 kDa
Observed Molecular Weight
40 kDa
Isotype
IgG1
Curated Selection
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