TCR beta Antibody [H57-597]

The alphabeta TCR is expressed on T lymphocytes of all mouse strains tested. The H57-597 monoclonal antibody does not react with gammadelta TCR-bearing cells. Plate-bound or soluble H57-597 activates alphabeta TCR-bearing T cells. In vitro and in vivo, H57-597 can induce immature thymocytes to undergo apoptosis. In vivo administration of H57-597 has been shown to deplete alphabeta TCR-bearing cells to near completion and prevent graft rejection.

TCR beta Antibody [H57-597] for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, stimulaton, separation, and depletion assays.