Antitubercular agent-45

Antitubercular agent-45 (Compound 5g) is an antifungal and antitubercular agent. Antitubercular agent-45 inhibits S. aureus, MRSA, B. subtilis, E. coli, C. albicans with MIC values of 6.4, 10.8, 6.1, 8.4 , 8.1 μM respectively[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Bacterial; Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antitubercular-agent-45.html

Solubility

10 mM in DMSO

Smiles

O=C1S/C(C(N1C(C2=CC=C(C(F)(F)F)C=C2)=O)=O)=C\C3=CN=C(N=C3)C(F)(F)F

Molecular Formula

C17H7F6N3O3S

Molecular Weight

447.31

References & Citations

[1]Raghu MS, et al. Synthesis, biological evaluation and molecular docking study of pyrimidine linked thiazolidinedione derivatives as potential antimicrobial and antitubercular agents. Bioorg Med Chem Lett. 2024 May 1;103:129707.