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APLP2 (phospho Tyr755) Antibody

Product Specifications

Background

APLP2 May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3' (CDEI box) .

NCBI Gene ID

334

Swiss Prot

Q06481

Accession Number

NP_001633.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

APLP2 (phospho Tyr755) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 755 (P-T-Y (p) -K-Y) derived from Human APLP2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

86 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of APLP2 only when phosphorylated at tyrosine 755

Symbol

APLP2

NCBI Official Name

Amyloid beta (A4) precursor-like protein 2

NCBI Organism

Homo sapiens

Background Reference 01

Sprecher C.A., Biochemistry 32:4481-4486 (1993) .

Background Reference 02

Wasco W., Nat. Genet. 5:95-99 (1993) .

Background Reference 03

Von der Kammer H., DNA Cell Biol. 13:1137-1143 (1994) .

Other Product Names

Amyloid protein homolog , Amyloid-like protein 2 precursor, APP2, APPH, CDEI-box binding protein

Tested Applications

IHC

Protein ID

214010181

Physical Properties

Liquid

Curated Selection

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