CD29 Antibody [TS2/16] (FITC)

Product Specifications

Background

The TS2/16 moncolonal antibody specifically reacts with human CD29 (Integrin beta1), a 130 kDA type I glycoprotein expressed on hematopoietic and non-hematopoietic cells. It forms the VLA- (1-6) molecules with integrin alpha- (1-6) and is involved in the adhesion between cell-cell and cell-matrix. The TS2/16 antibody has been found to activate beta 1 integrins.

NCBI Gene ID

3688

Swiss Prot

P05556

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

TS2/16

Conjugation

FITC

Type

Primary Antibodies

Field of Research

Cancer

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Mouse IgG1, kappa

Specificity

The TS2/16 moncolonal antibody specifically reacts with human CD29 (Integrin beta1), a 130 kDA type I glycoprotein expressed on hematopoietic and non-hematopoietic cells.

Symbol

ITGB1

NCBI Official Name

Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)

NCBI Organism

Homo sapiens

Background Reference 01

Hemler, M. E., Sanchez-Madrid, F., Flotte, T. J., Krensky, A. M., Burakoff, S. J., Bhan, A. K., ... Strominger, J. L. (1984) . Glycoproteins of 210,000 and 130,000 mw on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell lines.The Journal of Immunology,132 (6), 3011-3018.

Background Reference 02

Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

Background Reference 03

Sanchez-Madrid, F., Krensky, A. M., Ware, C. F., Robbins, E., Strominger, J. L., Burakoff, S. J., Springer, T. A. (1982) . Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3.Proceedings of the National Academy of Sciences,79 (23), 7489-7493.