EWSR1 Antibody (Center) [APR32964G]
Product Specifications
Background
Tissue Location: Ubiquitous.
Synonyms
RNA-binding protein EWS, EWS oncogene, Ewing sarcoma breakpoint region 1 protein, EWSR1, EWS
Gene Name
EWSR1
Gene ID
2130
UniProt
Q01844
Chromosomal Location
Nucleus. Cytoplasm. Cell membrane. Note=Relocates from cytoplasm to ribosomes upon PTK2B/FAK2 activation
Applications
WB
Dilution
WB--1:1000
Function
Might normally function as a transcriptional repressor. EWS- fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.
Molecular Weight
68478
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EWSR1 Antibody (Center) [APR32964G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=2130
Uniprot URL
https://www.uniprot.org/uniprot/Q01844
Available Sizes
Curated Selection
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