Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

NFkB p105 / p50 (Ab 932) Antibody

Product Specifications

Background

NF-κ -B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-κ -B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.

NCBI Gene ID

4790

Swiss Prot

P19838

Accession Number

NP_001158884.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

NFkB-p105/p50 (Ab-932) antibody was raised against a peptide sequence around aa.930~934 (E-T-S-F-R) derived from Human NFκ B-p105.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=79-381

Calculated Molecular Weight

50, 120 kDa

Specificity

This antibody detects endogenous level of total NFκ B-p105/p50 protein.

Applications Notes

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Symbol

NFKB1

NCBI Official Name

Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

NCBI Organism

Homo sapiens

Background Reference 01

Soren Beinke et al. (2004) Biochem J. 382 (Pt 2) : 393–409. Vigo Heissmeyer1, et al. (1999) The EMBO Journal 18: 4766–4778, F Chen, et al. (2006) Cell Death and Differentiation 13: 1835–1838. Kris A. Steinbrecher, et al. (2005) Mol Cell Biol. 25 (19) : 8444–8455.

Other Product Names

P50, KBF1, p105, EBP-1, NF-kB1, NFKB-p50, NFkappaB, NF-kappaB, NFKB-p105, NF-kappa-B, PRMT4, DNA-binding factor KBF1, NF-kappa-B1 p84/NF-kappa-B1 p98, NFKB1, NFkB-p50

Tested Applications

WB, IHC

Protein ID

259155302

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Rabbit Monoclonal ROS Antibody (ROS1/8268R) [Biotin]
NBP3-20759B 0.1 mL

Rabbit Monoclonal ROS Antibody (ROS1/8268R) [Biotin]

Ask
View Details
Anti-PDGFRB/CD140b Reference Antibody (rinucumab)
MBS9247181-01 0.1 mg

Anti-PDGFRB/CD140b Reference Antibody (rinucumab)

Ask
View Details
Anti-PDGFRB/CD140b Reference Antibody (rinucumab)
MBS9247181-02 5x 0.1 mg

Anti-PDGFRB/CD140b Reference Antibody (rinucumab)

Ask
View Details
CNGA2 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
16452111 3 x 1.0 µg

CNGA2 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

Ask
View Details
UTY Antibody, FITC conjugated
MBS7107121-01 0.05 mg

UTY Antibody, FITC conjugated

Ask
View Details
UTY Antibody, FITC conjugated
MBS7107121-02 0.1 mg

UTY Antibody, FITC conjugated

Ask
View Details