Stathmin 1 (phospho Ser16) Antibody

Product Specifications

Background

Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear.

NCBI Gene ID

3925

Swiss Prot

P16949

Accession Number

NP_001138926.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Stathmin 1 (Phospho-Ser16) antibody was raised against a peptide sequence around phosphorylation site of serine 16 (R-A-S (p) -G-Q) derived from Human Stathmin 1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

19 kDa

Specificity

This antibody detects endogenous level of Stathmin 1 only when phosphorylated at serine 16.

Applications Notes

I+H157mmunohistochemistry: 1:50~1:100

Symbol

STMN1

NCBI Official Name

Stathmin 1

NCBI Organism

Homo sapiens

Background Reference 01

Larsson N, et al. (1999) Mol Cell Biol; 19 (3) : 2242-2250Küntziger T, et al. (2001) Mol Biol Cell; 12 (2) : 437-448Vadlamudi RK, et al. (2005) Mol Cell Biol; 25 (9) : 3726-3736Vázquez-Boland JA, et al. (2001) Clin Microbiol Rev; 14 (3) : 584-640Howell B, et al. (1999) Mol Biol Cell; 10 (1) : 105-118