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EGFR WT/T790M-IN-2

Product Specifications

Target

Apoptosis|||EGFR

Related Pathways

Apoptosis|||JAK/STAT signaling|||Angiogenesis|||Tyrosine Kinase/Adaptors

Bioactivity

EGFRWT/T790M-IN-2 (Compound 7c) is an inhibitor of EGFR T790M/WT with IC50 values of 0.08 and 0.13 ?M, respectively. This compound induces apoptosis by arresting the cell cycle at the G0-G1 phase and demonstrates antitumor activity.

Molecular Formula

C19H13ClFN5S

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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