CD4 Antibody [B486A1]
Product Specifications
Background
The CD4 antigen is highly expressed on human T helper cells and thymocytes, and at lower levels on monocytes and dendritic cells. This integral membrane glycoprotein of approximately 58 kDa contains four external domains (D1 to D4) that show homology to members of the immunoglobulin (Ig) superfamily. It is responsible for the recognition of the MHC class II antigen. The CD4 antibody recognizes most thymocytes and about 65% of peripheral blood T cells.
NCBI Gene ID
920
Swiss Prot
P01730
Accession Number
NP_000607.1
Host
Mouse
Reactivity
Human
Immunogen
Ni-NTA purified recombinant human CD4 expressed in E. Coli strain BL21 (DE3) .
Clonality
Monoclonal
Clone
B486A1
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
Antibody is purified by protein A affinity chromatography.
Concentration
Batch dependent
Buffer
Purified antibody in PBS containing 0.03% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
CD4 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG1
Symbol
CD4
NCBI Official Name
CD4 molecule
NCBI Organism
Homo sapiens
Background Reference 01
M Benkirane J Virol. 1995 November; 69 (11) : 6898¨C6903.
Other Product Names
CD4mut
Tested Applications
ELISA, WB, IHC
Protein ID
10835167
Curated Selection
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