ZRANB1 Antibody

Product Specifications

Background

ZRANB1 is a positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. It acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription and may also modulate TNF-alpha signaling.

NCBI Gene ID

54764

Swiss Prot

Q9UGI0

Accession Number

Q9UGI0

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This ZRANB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 665-692 amino acids from the C-terminal region of human ZRANB1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

81 kDa

Fragment

Rabbit Ig

Symbol

ZRANB1

NCBI Official Name

Ubiquitin thioesterase ZRANB1

NCBI Organism

Homo sapiens

Background Reference 01

Tran, H., et al. Genes Dev. 22 (4) :528-542 (2008)

Background Reference 02

Evans, P.C., et al. Biochem. J. 357 (PT 3), 617-623 (2001)

Other Product Names

Ubiquitin thioesterase ZRANB1, TRAF-binding domain-containing protein, hTrabid, Zinc finger Ran-binding domain-containing protein 1, ZRANB1, TRABID

Tested Applications

WB, IHC-P

Protein ID

212276487

Physical Properties

Liquid

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