STING agonist-12
Product Specifications
CAS Number
2259624-71-8
Target
STING
Related Pathways
Immunology/Inflammation
Purity
0.9829
Bioactivity
STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalised and primary cells and a cytokine induction fingerprint consistent with STING activation.
Smiles
CC1(C)C(=O)N(Cc2c(F)cccc2Cl)c2cc(ccc12)C(=O)NCc1c(F)cc(F)cc1F
Molecular Formula
C25H19ClF4N2O2
Molecular Weight
490.88
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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