CAPN3 Antibody
Product Specifications
Background
Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A.
NCBI Gene ID
825
Swiss Prot
P20807
Accession Number
P20807
Host
Rabbit
Reactivity
Human
Immunogen
This CAPN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 603-632 amino acids from the C-terminal region of human CAPN3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
94 kDa
Fragment
Rabbit Ig
Symbol
CAPN3
NCBI Official Name
Calpain-3
NCBI Organism
Homo sapiens
Background Reference 01
Charlton, R., et al. Neuromuscul. Disord. 19 (7) :449-457 (2009)
Background Reference 02
Moretti, D., et al. Carcinogenesis 30 (6) :960-967 (2009)
Background Reference 03
Enjuanes, A., et al. Cancer Res. 68 (24) :10178-10186 (2008)
Background Reference 04
Beckmann, J.S., et al. Neuromuscul. Disord. 18 (12) :913-921 (2008)
Other Product Names
Calpain-3, Calcium-activated neutral proteinase 3, CANP 3, Calpain L3, Calpain p94, Muscle-specific calcium-activated neutral protease 3, New calpain 1, nCL-1, CAPN3, CANP3, CANPL3, NCL1
Tested Applications
WB, IHC-P, Flow
Physical Properties
Liquid
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
bs-2608R-PE-Cy5-01 20 µL
IL-17RD Polyclonal Antibody, PE-Cy5 Conjugated
Sign In for Pricing
View Details