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PRUNE Antibody

Product Specifications

Background

Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. It plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1.

NCBI Gene ID

58497

Swiss Prot

Q86TP1

Accession Number

Q86TP1

Host

Rabbit

Reactivity

Human

Immunogen

This PRUNE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 360-389 amino acids from the C-terminal region of human PRUNE.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=64-092

Calculated Molecular Weight

50 kDa

Fragment

Rabbit Ig

Symbol

PRUNE

NCBI Official Name

Protein prune homolog

NCBI Organism

Homo sapiens

Background Reference 01

Vieira, A.R., et al. Genet. Med. 10 (9) :668-674 (2008)

Background Reference 02

Middelhaufe, S., et al. Biochem. J. 407 (2) :199-205 (2007)

Background Reference 03

Kobayashi, T., et al. Mol. Cell. Biol. 26 (3) :898-911 (2006)

Background Reference 04

Zollo, M., et al. Clin. Cancer Res. 11 (1) :199-205 (2005)

Other Product Names

Protein prune homolog, hPrune, Drosophila-related expressed sequence 17, DRES-17, DRES17, HTcD37, PRUNE

Tested Applications

WB, IHC-P, Flow

Protein ID

229462737

Physical Properties

Liquid

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