PSMG2 Antibody

Product Specifications

Background

Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.

NCBI Gene ID

56984

Swiss Prot

Q969U7

Accession Number

Q969U7

Host

Rabbit

Reactivity

Human

Immunogen

This PSMG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-246 amino acids from the C-terminal region of human PSMG2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

29 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PSMG2

NCBI Official Name

Proteasome assembly chaperone 2

NCBI Organism

Homo sapiens

Background Reference 01

Cooper, J.D., et al. Nat. Genet. 40 (12) :1399-1401 (2008)

Background Reference 02

Barrett, J.C., et al. Nat. Genet. 40 (8) :955-962 (2008)

Background Reference 03

Miyagawa, H., et al. Rheumatology (Oxford) 47 (2) :158-164 (2008)

Background Reference 04

Parkes, M., et al. Nat. Genet. 39 (7) :830-832 (2007)

Other Product Names

Proteasome assembly chaperone 2, PAC-2, Hepatocellular carcinoma-susceptibility protein 3, Tumor necrosis factor superfamily member 5-induced protein 1, PSMG2 {ECO:0000312|EMBL:AAH133561}