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JUP Antibody

Product Specifications

Background

JUP is a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.

NCBI Gene ID

3728

Swiss Prot

P14923

Accession Number

P14923

Host

Rabbit

Reactivity

Human

Immunogen

This JUP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 636-663 amino acids from the C-terminal region of human JUP.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

82 kDa

Fragment

Rabbit Ig

Symbol

JUP

NCBI Official Name

Junction plakoglobin

NCBI Organism

Homo sapiens

Background Reference 01

Arnemann, J., et.al., Genomics 10 (3), 640-645 (1991)

Other Product Names

Junction plakoglobin, Catenin gamma, Desmoplakin III, Desmoplakin-3, JUP, CTNNG, DP3

Tested Applications

WB, IHC-P, Flow

Protein ID

205371866

Physical Properties

Liquid

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