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PCM-1 Antibody

Product Specifications

Background

PCM-1 is required for centrosome assembly and function. This protein is essential for the correct localization of several centrosomal proteins including CEP250, CETN3, PCNT and NEK2. The protein is required to anchor microtubules to the centrosome.

NCBI Gene ID

5108

Swiss Prot

Q15154

Accession Number

Q15154

Host

Rabbit

Reactivity

Human

Immunogen

This PCM-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1816-1845 amino acids from the C-terminal region of human PCM-1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

229 kDa

Fragment

Rabbit Ig

Symbol

PCM1

NCBI Official Name

Pericentriolar material 1 protein

NCBI Organism

Homo sapiens

Background Reference 01

Balczon R., Bao L.J. Cell Biol. 124:783-793 (1994)

Background Reference 02

Corvi R., Berger N.Oncogene 19:4236-4242 (2000)

Background Reference 03

Dammermann A., Merdes A.J. Cell Biol. 159:255-266 (2002)

Background Reference 04

Reiter A., Walz C.Cancer Res. 65:2662-2667 (2005)

Other Product Names

Pericentriolar material 1 protein, PCM-1, hPCM-1, PCM1

Tested Applications

WB, IHC-P, Flow

Protein ID

296439495

Physical Properties

Liquid

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