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Atezolizumab

Product Specifications

UNSPSC Description

Atezolizumab (MPDL3280A) is a selective humanized monoclonal IgG1 antibody against programmed death ligand 1 (PD-L1), used for cancer research.

Target Antigen

Apoptosis; Autophagy; PD-1/PD-L1

Type

Inhibitory Antibodies

Related Pathways

Apoptosis;Autophagy;Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Anti-PD-L1_Neutralizing_Antibody.html

Purity

99.50

Solubility

H2O

Smiles

[Atezolizumab]

References & Citations

[1]Cha E, et al. PD-L1 inhibition with MPDL3280A for solid tumors. Semin Oncol. 2015 Jun;42(3):484-7.|[2]Liu Z, et al. Targeting autophagy enhances atezolizumab-induced mitochondria-related apoptosis in osteosarcoma. Cell Death Dis. 2021;12(2):164. Published 2021 Feb 8.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P9904/Atezolizumab-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P9904/Atezolizumab-SDS-MedChemExpress.pdf

Clinical Information

Launched

CAS Number

1380723-44-3

Available Sizes

Curated Selection

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