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Guanylyl Cyclase alpha 2 Antibody

Product Specifications

Background

Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs.

NCBI Gene ID

2977

Swiss Prot

P33402

Accession Number

P33402

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Guanylyl Cyclase alpha 2 (GUCY1A2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 105-136 amino acids from the N-terminal region of human Guanylyl Cyclase alpha 2 (GUCY1A2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=62-678

Calculated Molecular Weight

82 kDa

Fragment

Rabbit Ig

Symbol

GUCY1A2

NCBI Official Name

Guanylate cyclase soluble subunit alpha-2

NCBI Organism

Homo sapiens

Background Reference 01

Baba, H., et al., Neuroreport 15 (4) :677-680 (2004) .

Background Reference 02

Bellamy, T.C., et al., Proc. Natl. Acad. Sci. U.S.A. 99 (1) :507-510 (2002) .

Background Reference 03

Russwurm, M., et al., J. Biol. Chem. 276 (48) :44647-44652 (2001) .

Background Reference 04

Bamberger, A.M., et al., J. Clin. Endocrinol. Metab. 86 (2) :909-912 (2001) .

Other Product Names

Guanylate cyclase soluble subunit alpha-2, GCS-alpha-2, GUCY1A2, GUC1A2, GUCSA2

Tested Applications

WB, IHC-P

Protein ID

461897

Physical Properties

Liquid

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